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Aurora B-mediated phosphorylation at S145 selectively disrupts Sororin binding to Pds5 while preserving its engagement with the RAD21-SMC3 gate

Higher quality studies with larger samples should be performed to confirm the results

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As a result, clinical modification of oxygen tension in an individual may have therapeutic implications in terms of slowing down the ageing process

Mller M, Wang Y, Squillante MR, Held KD, Anderson RR, Purschke M